The battle for Champions League qualification continues with fourth-placed Aston Villa away to Luton Town on Saturday and Tottenham Hotspur, who are five points behind with a game in hand, hosting Crystal Palace.
A round-up of Saturday's action in the Premier League.
Manchester United stretched their winless Premier League streak to four games after their manager Jose Mourinho and midfielder Ander Herrera were sent off in a 0-0 home draw with Burnley on Saturday.
Man U players Ryan Giggs and Christiano Ronaldo have been fined by the FA for their part in a fracas during and after a Premier League game against Arsenal.
Ryan Giggs enjoyed a dream 900th appearance by scoring a late winner in Manchester United's 2-1 win at Norwich City while Arsenal came from behind to thump Tottenham Hotspur 5-2 in the Premier League on Sunday.
Manchester City went 11 points clear with a record 14th consecutive Premier League win in an entertaining derby against Manchester United at Old Trafford.
Marcus Rashford continued his fine season as he scored again to help Manchester United beat Nottingham Forest 3-0 in their League Cup semi-final first leg on Wednesday.
Arsenal's title hopes hit with 2-0 loss to Villa as Man City get boost
Images from Saturday's Premier League action.
High drama ensued during the English Premier League matches on Wednesday as Spurs manager Jose Mourinho was booked while Brighton stunned Chelsea via Alireza Jahanbakhsh's superb equaliser to deny the Blues victory. Here is all the EPL action in IMAGES from Wednesday's matches.
Manchester City manager Pep Guardiola was furious at several decisions during the 2-1 loss at St James' Park and appeared to take out his frustration on a pitch-side TV cameraman after the final whistle.
A summary of Sunday's action in the English Premier League.
Dutch striker Robin van Persie enjoyed an eventful return to his old club Arsenal for the first time when he scored and was booked as champions Manchester United held the Londoners to a 1-1 draw at the Emirates.
Images from the English Premier League matches played on Saturday.
Liverpool strolled to a 2-0 victory over Brentford, while Newcastle drew 1-1 at Bournemouth.
Manchester United manager Louis van Gaal will delve into the depths of his squad for the visit to Arsenal in the Premier League on Saturday, as an injury crisis engulfs Old Trafford.
Cristiano Ronaldo scored on his return to the starting line-up as Manchester United sealed a place in the Europa League knock-out rounds with a 3-0 victory over Sheriff Tiraspol at Old Trafford on Thursday.
Images from Saturday's action in the Premier League.
Thierry Henry has been named head coach of the country's Under-21s until 2025
Manchester United and Arsenal, who have scored and conceded a total of 41 goals between them in eight matches since October 20, promise a feast of football on Saturday as Robin van Persie faces his ex-club for the first time.
It took 10 Premier League games for the first cracks to appear in Manchester City's facade last season, but Pep Guardiola got a much earlier reminder of his side's fall from grace on Saturday in another defeat to Tottenham Hotspur.
IMAGES from the EPL matches played on Saturday
Late goals by Robin van Persie and Thierry Henry gave Arsenal a thrilling 2-1 win over Manchester United on Sunday, shattering the visitors' bid to open a nine-point lead in the Premier League.
Manchester United bolstered their squad with a flurry of transfer deadline day signings, Manchester City and Liverpool also splashed out while ambitious Brighton & Hove Albion sealed an audacious loan deal for Barcelona's Ansu Fati on Friday.
Arsenal beat Manchester City 4-1 in a penalty shootout to win the Community Shield on Sunday
Arsenal will reportedly play Chelsea in a fourth-round Capital One Cup match after winning 4-3 on penalties against West Bromwich Albion on Wednesday at The Hawthorns.
Manchester City's spending of more than 180 million pounds ($223.58 million) was the second-biggest outlay ever worldwide by a club in the January transfer window.
Arsenal are going through a sticky patch, goals and points are drying up and injuries are mounting, so it is not the best time to entertain Manchester United on Saturday. Chelsea, who returned to the top last week on goal difference with a 5-0 thrashing of Sunderland, are at Blackburn Rovers on Sunday while Liverpool, stunned 2-1 at Tottenham Hotspur, are at home to West Bromwich Albion on Saturday.
Manchester United kept their treble dreams alive by knocking Arsenal out of the FA Cup five days after the London side's Champions League exit thanks to a deserved 2-0 quarter-final win at Old Trafford on Saturday.
Images from Saturday's action in the Premier League.
Manchester United forward Robin van Persie is unlikely to be fit for the Premier League derby match against Manchester City later this month, manager Louis van Gaal said on Friday.
The Premier League bursts back into life after the international break.
Arsenal survived a massive scare as they registered a thrilling Premier League win over Bournemouth to remain on top of the table.
IMAGES from the Premier League matches played on Saturday.
Pierre-Emerick Aubameyang scored twice to earn Arsenal a 3-2 Premier League win over Everton on Sunday, extending the Gunners' unbeaten start to 2020 and moving them back into the battle for European places. The win lifts Mikel Arteta's Arsenal side up to ninth place in the league with 37 points, while Everton remain without a victory at the Gunners in 24 years and a point adrift in 11th.
Cristiano Ronaldo passed the 800-goal mark for club and country, scoring twice as Manchester United beat Arsenal 3-2 in an incident-packed Premier League match on Thursday.
Riyad Mahrez scored a hat-trick as Manchester City snapped their losing streak in FA Cup semi-finals with a 3-0 stroll over second-tier Sheffield United at Wembley on Saturday.
Sergio Aguero scored twice as Manchester City thrashed Manchester United 4-1 in the Premier League at the Etihad stadium on Sunday.
Sergio Aguero scored twice as Manchester City thrashed Manchester United 4-1 in the Premier League at the Etihad stadium on Sunday.
Liverpool moved back to the top of the Premier League with a 2-0 victory at struggling Burnley